白化大鼠体内的儿茶酚胺与操作性反应率
Catecholamines and operant response rates in albino rats.
作者信息
Will B, Maurissen J, Ropartz P
出版信息
Psychopharmacol Commun. 1976;2(3):219-29.
The action of d-amphetamine was studied in rats conditioned on an operant "multiple" schedule of reinforcement. The action of this drug depended on the control response rate of each individual. The turnover of brain norepinephrine (NE) and dopamine (DA) was estimated in the whole brain of the same rats; the steady state level of NE, but not the turnover time, was significantly correlated with the average response rate of each subject. No significant correlation was found between this response rate and the turnover of DA. It is proposed that the response rate dependent effects of d-amphetamine might be related to brain NE levels.
在按照操作性“多重”强化程序训练的大鼠中研究了右旋苯丙胺的作用。这种药物的作用取决于每只大鼠的对照反应率。在同一只大鼠的全脑中估计了脑去甲肾上腺素（NE）和多巴胺（DA）的更新率；NE的稳态水平而非更新时间与每个实验对象的平均反应率显著相关。未发现该反应率与DA更新率之间存在显著相关性。有人提出，右旋苯丙胺的反应率依赖性效应可能与脑NE水平有关。
Zotero 插件