Johansson C, Ekelund K, Rubios C
Scand J Gastroenterol. 1976;11(7):729-34.
The gastric and intestinal response to a standard meal was examined with a quantitative multiple indicator dilution technique in a patient with jejunitis and malabsorption. Examinations were made during and after recovery from disease. The malabsorptive state was associated with a marked delay of the gastric emptying paralleled by a low gastric secretion rate. Despite the low delivery rate from the stomach, large fluid volumes passed at the investigated level 70 cm distal to the pyloric sphincter. This was due to a reduced absorption of nutrients and water during a rapid transit of the proximal intestine and to persistently high pancreatic and intestinal secretion rates. A comparison with data from the healthy experiment suggests that the strong gastric inhibition during malabsorption works as an effective compensation for the decreased absorptive capacity after the second hour from meal intake and onwards.
采用定量多指标稀释技术，对一名患有空肠炎和吸收不良的患者进食标准餐后的胃肠反应进行了检查。在疾病发作期间及恢复后均进行了检查。吸收不良状态与胃排空明显延迟相关，同时胃分泌率较低。尽管胃的排空率较低，但在幽门括约肌远端70厘米处的研究水平仍有大量液体通过。这是由于近端肠道快速转运期间营养物质和水分的吸收减少，以及胰腺和肠道分泌率持续较高所致。与健康实验数据的比较表明，吸收不良期间强烈的胃抑制作用可有效补偿进食后第二小时及以后吸收能力的下降。
