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维脑路通对大鼠肺放射性早期损伤的影响。

Effects of Venoruton on early postradiation damage in the lungs of rats.

作者信息

Starosławska E, Donica H, Sobolewski K, Floriańczyk B, Grzybowska-Szatkowska L A, Krzyzanowski K

机构信息

Oncological Centre of Lublin, Medical Academy of Białystok.

出版信息

Rocz Akad Med Bialymst. 1998;43:95-109.

PMID:9972046
Abstract

The study aimed at testing the effects of Venoruton on the early postradiation damage in the lungs of rats. The chests of the rats were irradiated with Co-60, fractional dose 250 cGy/DD, total dose 2500 cGy/DD. Venoruton was given intraperitoneally, in quantities of 0.1 ml once daily for 90 days. The experiment have proved that Venoruton lowers the intensity of the early postradiation changes, mainly those which depend on the vascular damage.

摘要

该研究旨在测试维脑路通对大鼠肺部辐射后早期损伤的影响。用钴-60对大鼠胸部进行照射,分次剂量为250厘戈瑞/天,总剂量为2500厘戈瑞/天。维脑路通通过腹腔注射给药,剂量为0.1毫升/天,持续90天。实验证明,维脑路通可降低辐射后早期变化的强度,主要是那些依赖于血管损伤的变化。

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