ε-氨基己酸衍生物对肝素抗凝活性的影响。
The influence of epsilon-aminocaproic acid derivatives on the anticoagulant activity of heparin.
作者信息
Midura-Nowaczek K, Bruzgo I, Worowski K, Roszkowska-Jakimiec W
机构信息
Institute of Chemistry, University of Bialystok, Poland.
出版信息
Rocz Akad Med Bialymst. 1998;43:228-31.
PMID:9972059
Abstract
Derivatives of epsilon-aminocaproic acid with antifibrinolytic activity, at low concentration, do not influence the anticoagulant activity of heparin under the heparin-thrombin test conditions. At concentrations higher than 0.002 M tested compounds slightly enhance the anticoagulant action of heparin.
摘要
具有抗纤维蛋白溶解活性的ε-氨基己酸衍生物，在低浓度下，在肝素-凝血酶测试条件下不影响肝素的抗凝活性。在高于0.002M的浓度下，受试化合物会轻微增强肝素的抗凝作用。
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