Fredman B, Nun M B, Zohar E, Iraqi G, Shapiro M, Gepstein R, Jedeikin R
Department of Anesthesiology and Intensive Care, Meir Hospital, Kfar Saba, Israel.
Anesth Analg. 1999 Feb;88(2):367-72.
Epidural steroids are commonly administered in the treatment of "failed back surgery syndrome." Because patient response is dependent on accurate steroid placement, fluoroscopic guidance has been advocated. However, because of ever-increasing medical expenditures, the cost-benefit of routine fluoroscopy should be critically evaluated. Therefore, 50 patients were enrolled into this institutional review board-approved, prospective, controlled, single-blinded study. At a predetermined intervertebral level, the epidural space was identified using an air loss of resistance technique. Thereafter, an epidural catheter was inserted 2 cm through the epidural needle. To determine the accuracy of the clinical placement, contrast medium was administered through the epidural catheter; antero-posterior and lateral lumbar spine radiographs were then obtained. The number of attempts required to successfully locate the epidural space, the reliability of the air loss of resistance technique in indicating successful epidural penetration in failed back surgery syndrome, the ability of the clinician to accurately predict the intervertebral space at which the epidural injection was performed, and the spread of contrast medium within the epidural space were recorded. A total of 48 epidurograms were performed. The number of attempts to successfully enter the epidural space was 2 +/- 1. In 44 cases, the radiological studies confirmed the clinical impression that the epidural space had been successfully identified. In three patients, the epidural catheter was in the paravertebral tissue. One myelogram was recorded. In 25 patients, the epidural catheter did not pass through the predetermined intervertebral space. In 35 cases, the contrast medium did not reach the level of pathology.
The clinical sign of loss of resistance is a reliable indicator of epidural space penetration in most cases of "failed back surgery syndrome." However, surface anatomy is unreliable and may result in inaccurate steroid placement. Finally, despite accurate placement, the depot-steroid solution will spread to reach the level of pathology in only 26% of cases.
硬膜外注射类固醇常用于治疗“腰椎手术失败综合征”。由于患者的反应取决于类固醇的准确注射位置,因此提倡使用荧光镜引导。然而,由于医疗费用不断增加,常规荧光镜检查的成本效益应进行严格评估。因此,50名患者被纳入这项经机构审查委员会批准的前瞻性对照单盲研究。在预定的椎间水平,使用空气阻力消失技术确定硬膜外间隙。此后,通过硬膜外针将硬膜外导管插入2厘米。为了确定临床放置的准确性,通过硬膜外导管注入造影剂;然后获得腰椎前后位和侧位X线片。记录成功定位硬膜外间隙所需的尝试次数、空气阻力消失技术在“腰椎手术失败综合征”中指示硬膜外穿刺成功的可靠性、临床医生准确预测硬膜外注射所进行的椎间间隙的能力以及造影剂在硬膜外间隙内的扩散情况。总共进行了48次硬膜外造影。成功进入硬膜外间隙的尝试次数为2±1次。在44例中,放射学研究证实了临床印象,即硬膜外间隙已成功识别。在3例患者中,硬膜外导管位于椎旁组织中。记录了1例脊髓造影。在25例患者中,硬膜外导管未穿过预定的椎间间隙。在35例中,造影剂未到达病变水平。
在大多数“腰椎手术失败综合征”病例中,阻力消失的临床体征是硬膜外间隙穿刺的可靠指标。然而,体表解剖不可靠,可能导致类固醇注射位置不准确。最后,尽管放置准确,但长效类固醇溶液仅在26%的病例中扩散至病变水平。