de Oliveira J M
Serviço de Cirurgia Cardiotorácica, Hospitais da Universidade, Coimbra.
Rev Port Cardiol. 1998 Dec;17(12):967-73.
At present, the treatment for acute myocardial infarction is revascularization during the critical initial period of six hours after the beginning of coronary occlusion. Despite the fact that surgery performed within this time period presents a hospital of mortality around 2%, and with excellent results in the long term, it is seldom used due to logistic limitations and capabilities of hospital infrastructures, high costs and the possibility of the surgical team initiating surgery inside the useful time period. Surgery is thus limited to the patients with suitable anatomy, who are not candidates or had failure of thrombolytic/angioplasty therapy and are in the six-hour period after initiation of symptoms. Surgery performed at a later stage has good results if performed in a non emergency situation, specially after the first 72 hours. Surgery continues to be the only treatment for the mechanical complications of infarction, and good results have recently been shown in ventricular septal ruptures, with hospital mortality of 14%, due to the use of an endoventricular patch in patients operated early, before the consequences of low cardiac output develop at systemic level. In the surgical treatment of mitral regurgitation, the tendency has been to use repair techniques whenever possible, but still with hospital mortality up to 15%. The recent advances of the techniques and tactics of myocardial preservation during surgery have made a very significant contribution to the better results we see today.
目前,急性心肌梗死的治疗方法是在冠状动脉闭塞开始后的关键最初6小时内进行血运重建。尽管在此时间段内进行手术的医院死亡率约为2%,且长期效果良好,但由于后勤限制、医院基础设施能力、成本高昂以及手术团队在有效时间段内启动手术的可能性等原因,该方法很少使用。因此,手术仅限于解剖结构合适、不适合溶栓/血管成形术治疗或治疗失败且症状出现后6小时内的患者。如果在非紧急情况下进行,特别是在症状出现72小时后进行,后期手术也会有良好效果。手术仍然是梗死机械性并发症的唯一治疗方法,最近在室间隔破裂的治疗中显示出良好效果,由于在患者出现低心输出量的全身后果之前尽早进行手术并使用心室内补片,医院死亡率为14%。在二尖瓣反流的外科治疗中,倾向于尽可能使用修复技术,但医院死亡率仍高达15%。手术期间心肌保护技术和策略的最新进展为我们如今看到的更好治疗效果做出了非常重要的贡献。