Kabukcuoglu Y, Grimer R J, Tillman R M, Carter S R
Orthopaedic Department, Sisli Etfal Hospital, Turkey.
Clin Orthop Relat Res. 1999 Jan(358):8-14.
Fifty-four patients had endoprosthetic replacement of the proximal femur after resection of primary malignant or aggressive bone tumors. The mean age of the patients was 41 years. The average duration of followup was 9 years (range, 5-24 years). At the time of this review 35 patients are surviving. There were six revisions of the acetabulum and seven revisions of the femoral component. The survivorship of the prostheses without revision was 77% at 10 years falling to 57% at 20 years. There was a 13% risk of amputation and a 1.8% incidence of infection. The mean of the functional scores of the 35 living patients was 83% (range, 60%-97%). This study showed that successful long term results can be obtained with cemented massive endoprostheses despite the incidence of recognized complications including polyethylene wear and aseptic loosening.
54例患者在原发性恶性或侵袭性骨肿瘤切除术后接受了股骨近端的人工关节置换。患者的平均年龄为41岁。平均随访时间为9年(范围5 - 24年)。在本次回顾时,35例患者存活。髋臼翻修6例,股骨部件翻修7例。未翻修假体的10年生存率为77%,20年时降至57%。截肢风险为13%,感染发生率为1.8%。35例存活患者的功能评分平均为83%(范围60% - 97%)。本研究表明,尽管存在包括聚乙烯磨损和无菌性松动等公认并发症的发生率,但骨水泥型大型假体仍可获得成功的长期效果。