Frick G, Frick U, Brügmann E
Z Gesamte Inn Med. 1976 Aug 1;31(15):579-83.
Due to a slight haemooysis after the application of bromsulphalein an intravasal coagulation with reduction of the number of heparinocytes and an increase of fibrinolytic split products develops. These changes are to be observed in the vast majority of tests, also in such cases where no clinical signs of an incompatibility appear. Indocyanine-green does not cause these severe disturbances of coagulation. Slight changes are traced back to the examination technique. Patients with chronic liver disease already show increased values of fibrinolytic split products. In increased initial values of fibrinolytic split products bromsulphalein does not cause a further increase.
应用酚四溴酞磺酸钠后由于出现轻微溶血,会发生血管内凝血,伴有肝素细胞数量减少及纤维蛋白溶解分裂产物增加。在绝大多数试验中均可观察到这些变化,即便在未出现不相容临床体征的情况下亦是如此。吲哚菁绿不会引起这些严重的凝血紊乱。轻微变化可追溯至检查技术。慢性肝病患者的纤维蛋白溶解分裂产物值已经升高。纤维蛋白溶解分裂产物初始值升高时,酚四溴酞磺酸钠不会使其进一步升高。