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[体外条件下人体红细胞机械抗性的研究]

[Studies on the mechanical resistance of human erythrocytes under in-vitro conditions].

作者信息

Otto H H, Reuter W, Krastel V, Fleischer J

出版信息

Z Exp Chir. 1976 Oct;9(5):316-24.

PMID:997693
Abstract

Hemolysis and resistance of erythrocytes were studies in-vitro in experiments on human ACD fresh blood and on heparinized fresh blood after oxygen dispersion, resp. mixed oxygen and carbon dioxide dispersion, and subsequent treatment in the hemoresistometer. Blood alkalinity increases under oxygen dispersion, acidity increases under dispersion with mixed gases. The length of the period of dispersion is more important for hemolysis than the change of pH. The hematocrit value influences the behavior of blood resistance. High values imply enhanced hemolysis. There is no significant difference of actual hemolysis values between oxygen and oxygen/carbon dioxide dispersion. A different behavior appears in the calculation of difference value of hemolysis after treatment in resistometer and the respective actual hemolysis.

摘要

在人体ACD新鲜血液以及经氧气弥散、分别为混合氧气和二氧化碳弥散并随后在血液电阻计中进行处理后的肝素化新鲜血液的体外实验中,对红细胞的溶血和抗性进行了研究。氧气弥散时血液碱度增加,混合气体弥散时酸度增加。弥散时间对溶血比pH值变化更为重要。血细胞比容值影响血液抗性行为。高值意味着溶血增强。氧气弥散和氧气/二氧化碳弥散之间的实际溶血值无显著差异。在电阻计中处理后溶血差值的计算与各自实际溶血情况呈现出不同的行为。

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