Bohr H
Acta Orthop Scand. 1976 Oct;47(5):558-65. doi: 10.3109/17453677608988737.
The development of arthrotic-like changes following the resection of the cruciate ligaments in the knee joint of rabbits has been studied at intervals from 2 weeks to 10 months in 35 animals. Signs of cartilage degeneration were followed by changes in the subchondral bone, where formation of osteophytes and condensation took place. An increased vascular supply was demonstrated by microangiographic and scintigraphic investigations. The uptake of 18F and 99mTc-polyphosphate reached a maximal value about 2 months after the operation and then diminished despite further development of arthrotic changes.
在35只兔子的膝关节中，对切除交叉韧带后关节样变化的发展进行了研究，时间间隔从2周持续到10个月。软骨退变迹象之后是软骨下骨的变化，出现了骨赘形成和骨质硬化。微血管造影和闪烁扫描研究显示血管供应增加。18F和99mTc-多聚磷酸盐的摄取在术后约2个月达到最大值，然后尽管关节变化进一步发展，但摄取量却减少了。
