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精神分裂症患者兄弟姐妹的出生季节。对父母受孕习惯解释的一项检验。

Season of birth among siblings of schizophrenics. A test of the parental conception habits interpretation.

作者信息

McNeil T, Kaij L, Dzierzykray-Rogalska M

出版信息

Acta Psychiatr Scand. 1976 Oct;54(4):267-74. doi: 10.1111/j.1600-0447.1976.tb00120.x.

Abstract

Many studies have shown schizophrenics to be born with unusual frequency in the period January-April, and one interpretation of this seasonality of birth is that the parents of schizophrenics have an unusually strong general tendency to conceive offspring who will be born in January-April. This parental conception habits interpretation may be tested by studying whether the siblings of schizophrenics are also born with increased frequency in January-April. The present study investigated the season of birth of 288 full siblings and 44 half-siblings in 91 families of male schizophrenics. Approximately 5% of the siblings were known to be schizophrenic; with the schizophrenic siblings excluded from the analyses, the full siblings showed a birth pattern much closer (nonsignificant) to that of the schizophrenics than to that of the general population. Half-siblings showed January-April birth rates at or below the population level. Although the mechanisms responsible for the current results still remain unclear, the study suggests that seasonality of births of schizophrenics may be related to the parents' conception habits as well as to an etiological or triggering effect on the development of schizophrenia in the offspring.

摘要

许多研究表明,精神分裂症患者在1月至4月期间出生的频率异常高,对这种出生季节性的一种解释是,精神分裂症患者的父母普遍有一种异常强烈的倾向,即怀上在1月至4月出生的后代。这种关于父母受孕习惯的解释可以通过研究精神分裂症患者的兄弟姐妹在1月至4月出生的频率是否也增加来进行检验。本研究调查了91个男性精神分裂症患者家庭中288名全同胞和44名半同胞的出生季节。已知约5%的兄弟姐妹患有精神分裂症;在分析中排除患有精神分裂症的兄弟姐妹后,全同胞的出生模式比一般人群更接近(无统计学意义)精神分裂症患者的出生模式。半同胞的1月至4月出生率等于或低于总体水平。尽管导致当前结果的机制仍不清楚,但该研究表明,精神分裂症患者出生的季节性可能与父母的受孕习惯以及对后代精神分裂症发展的病因或触发作用有关。

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