裂脑猫慢性癫痫病灶的临床和电生理效应

Clinical and electrophysiological effects of chronic epileptic lesion in split-brain cats.

作者信息

Majkowski J, Pisarski W, Bilińska-Nigot B, Sobieszek A, Karliński A

出版信息

Acta Neurochir (Wien). 1976(23 Suppl):59-64. doi: 10.1007/978-3-7091-8444-8_11.

Abstract

The development of the clinical and EEG manifestations of intracortical alumina cream epileptogenic lesion is described in 14 split-brain cats. In 4 animals contralateral and/or ipsilateral, cortical and subcortical secondary epileptic foci were present. The results indicate that integrity of interhemispheric transfer through the corpus callosum and anterior and posterior commissures is not necessary for the transmission of epileptic activity to contralateral hemisphere. Partial epileptic seizures of Jacksonian type were observed in 6 cats. In 1 cat grand mal epileptic seizure developed. The possible mechanisms of secondary epileptic foci and generalized type of seizure are discussed.

摘要

本文描述了14只裂脑猫皮层内氧化铝乳膏致痫性病变的临床和脑电图表现的发展情况。4只动物出现了对侧和/或同侧的皮层及皮层下继发性癫痫灶。结果表明，通过胼胝体以及前后连合进行的半球间传递的完整性，对于癫痫活动向对侧半球的传播并非必要条件。6只猫出现了杰克逊型部分性癫痫发作。1只猫发生了癫痫大发作。文中讨论了继发性癫痫灶和全身性癫痫发作类型的可能机制。