Effectiveness and hazard of endomyocardial biopsy in dogs: comparison of two methods.

Two different methods of endomyocardial biopsy were evaluated. Compared to the Konno bioptome, a technique using a biopsy forceps originally designed for fiberoptic bronchoscopy and bronchial biopsy, passed through a No. 9 Fr. end-hole catheter, was easier to perform. The biopsy device is smaller than the Konno bioptome, has sharper teeth, and is easier to clean. The two techniques did not differ in arrhythmogenicity, hemorrhagic changes in the myocardium, or distortion of the specimens. Ventricular tachycardia as defined by three beats in a row was observed in 34 per cent. Epicardial hemorrhage was seen in nine of 14 animals, and the specimen distortion rate was 43 per cent. In one animal, perforation of the right ventricle and hemopericardium occurred.