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The fate of brominated soya oil in the animal body.

作者信息

James S P, Kestell P

出版信息

Xenobiotica. 1978 Sep;8(9):557-64. doi: 10.3109/00498257809061255.

DOI:10.3109/00498257809061255
PMID:99886
Abstract
  1. The bromine-containing material accumulated in tissues of rats dosed with brominated soya oil gradually decreased when the oil was no longer administered. 2. G.l.c. of the transesterified ether extracts of tissues from dosed animals showed 9,10-dibromostearic acid in extracts from fat, heart, kidney, liver and muscle with much smaller amounts of 9,10,12,13-tetrabromostearic acid in all extracts except that from liver. 3. An ether-soluble bromine-containing metabolite excreted by rats dosed with brominated soya oil was tentatively identified as 5,6-dibromosebacic acid. 4. The same metabolite was excreted by rabbits, rats and marmosets dosed with 9,10-dibromostearic acid.
摘要

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