Wohl P, Chadimová M, Englis M, Táborský P, Rossmann P, Matl I
Klinika nefrologie a Patologicko-anatomické pracovistĕ IKEM Praha.
Cas Lek Cesk. 1998 Nov 30;137(23):721-4.
The objective of the paper is to draw attention to a rare cause of rapidly progressing renal failure which developed in the course of four months as a result of light chain deposition disease. The authors submit two case-histories of the disease assessed by renal biopsy after previous clinical and laboratory suspicion of monoclonal gammapathy. In one patient in the sternal punctate plasmacytoma was diagnosed and in the second case it was not possible to detect any type of monoclonal gammapathy or another possible cause of disease. Renal failure was in both cases irreversible and both patients were enlisted in regular haemodialyzation treatment.
本文的目的是提请注意一种罕见的快速进展性肾衰竭病因,该病因是由轻链沉积病在四个月内发展而成。作者提交了两例该疾病的病例史,这两例病例在先前临床和实验室怀疑为单克隆丙种球蛋白病后,经肾活检评估。其中一例患者经胸骨穿刺诊断为浆细胞瘤,另一例则未检测到任何类型的单克隆丙种球蛋白病或其他可能的病因。两例患者的肾衰竭均不可逆,且均已开始定期血液透析治疗。