McRae S, Garcia B M
Department of Pathology and Immunology, London Health Science Centre, Ontario, Canada.
Acta Cytol. 1997 Jul-Aug;41(4 Suppl):1279-83. doi: 10.1159/000333520.
The urinary bladder is an uncommon site for primary oat cell carcinoma, with as few as 30 histologically diagnosed cases described in the literature. The first reported cytologic diagnosis was made in 1991.
A 76-year-old female presented with gross hematuria. Voided urine cytology showed small, dark cells with little visible cytoplasm and coarse chromatin. Subsequent histopathologic, immunopathologic and electron microscopic studies confirmed the diagnosis of primary oat cell carcinoma.
The diagnosis of oat cell carcinoma is well recognized in respiratory cytology. The same cells found in a urinary specimen may suggest a primary oat cell tumor in conjunction with negative clinical and radiologic investigations for a primary tumor elsewhere.
膀胱是原发性燕麦细胞癌的罕见发病部位，文献中仅有30例经组织学确诊的病例报道。首次经细胞学诊断的病例报告于1991年。
一名76岁女性因肉眼血尿就诊。尿液细胞学检查显示细胞体积小、颜色深，几乎看不到细胞质，染色质粗糙。随后的组织病理学、免疫病理学和电子显微镜研究证实了原发性燕麦细胞癌的诊断。
燕麦细胞癌的诊断在呼吸道细胞学中已得到广泛认可。在尿液标本中发现相同的细胞，结合其他部位原发性肿瘤的临床和影像学检查结果为阴性，可能提示原发性燕麦细胞肿瘤。
