Logrono R, Kurtycz D F, Sproat I A, Allan R W, Inhorn S L
University of Wisconsin State Laboratory of Hygiene, Madison, USA.
Acta Cytol. 1997 Jul-Aug;41(4 Suppl):1402-6. doi: 10.1159/000333549.
Desmoplastic small round cell tumor (DSRCT) is a recently described neoplasm characterized by aggressive biology, occurrence in body cavities, expression of antigens from multiple cell lineages and a specific translocation between chromosomes 11 and 22. Most of the published information on this neoplasm is histologic. The case presented here enabled presentation of the cytomorphologic and immunocytochemical features of aspirated cytologic material obtained from this unique tumor.
The cytologic, histologic, radiologic and clinical features of a DSRCT from a 17-year-old patient are presented. Although the initial diagnosis in this case was made on histology, recurrence was proven by fine needle aspiration biopsy (FNAB).
The presence of sheets or clusters of small round malignant cells, associated with shards of dense fibroconnective tissue, in FNAB should lead the cytologist to consider the diagnosis of DSRCT.
促结缔组织增生性小圆细胞肿瘤（DSRCT）是一种最近描述的肿瘤，其特征为生物学行为侵袭性、发生于体腔、表达多种细胞谱系的抗原以及11号和22号染色体之间的特异性易位。关于这种肿瘤的大多数已发表信息都是组织学方面的。本文所呈现的病例展示了从这种独特肿瘤获取的抽吸细胞学材料的细胞形态学和免疫细胞化学特征。
介绍了一名17岁患者的DSRCT的细胞学、组织学、放射学和临床特征。尽管该病例最初的诊断是基于组织学，但细针穿刺活检（FNAB）证实了复发。
在FNAB中出现成片或成簇的小圆形恶性细胞，并伴有致密纤维结缔组织碎片，应促使细胞学家考虑诊断为DSRCT。
