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男性生殖的激素调节(参考男性不育症)

Hormonal regulation of male reproduction (with reference to infertility in man).

作者信息

Courot M

出版信息

Andrologia. 1976;8(3):187-93. doi: 10.1111/j.1439-0272.1976.tb02134.x.

DOI:10.1111/j.1439-0272.1976.tb02134.x
PMID:999040
Abstract

In mammals, pituitary control of spermatogenesis varies with age. In the rat, before puberty FSH is highly active whereas LH is not; after puberty it seems that LH alone is able to support spermatogenesis. The mode of action of hormones is discussed. In the human, in case of infertility due to hypogonadotrophic hypogonadism, spermatogenesis can be restored by HCG or HMG. The best results are obtained after simultaneous treatment with both hormones, LH activity being predominant.

摘要

在哺乳动物中,垂体对精子发生的控制随年龄而变化。在大鼠中,青春期前促卵泡激素(FSH)高度活跃,而促黄体生成素(LH)则不然;青春期后,似乎仅LH就能支持精子发生。文中讨论了激素的作用方式。在人类中,对于因低促性腺激素性性腺功能减退导致的不育症,人绒毛膜促性腺激素(HCG)或人绝经期促性腺激素(HMG)可恢复精子发生。两种激素同时治疗后效果最佳,其中LH的活性起主要作用。

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引用本文的文献

1
Hypothalamic regulation of pituitary secretion of luteinizing hormone. II. Feedback control of gonadotropin secretion.下丘脑对垂体促黄体生成素分泌的调节。II. 促性腺激素分泌的反馈控制。
Bull Math Biol. 1980;42(1):57-78. doi: 10.1007/BF02462366.
2
Gonadotrophin treatment of pathospermic patients.用促性腺激素治疗精子异常的患者。
Int Urol Nephrol. 1984;16(3):259-63. doi: 10.1007/BF02082572.