Doroszkiewicz W, Cisowska A, Jankowski S, Koziorowski A, Murawski M
Institute of Microbiology, University of Wrocław, Poland.
Acta Microbiol Pol. 1998;47(3):275-81.
The susceptibility of Escherichia coli K1, Salmonella enteritidis, Salmonella typhimurium strains and their adaptative forms resistant to colistine (Colr forms) was compared with respect to their sensitivity to the bactericidal action of normal cord serum and normal bovine serum. It has been shown that the Colr forms are more susceptible to sera as compared to initial strains. The increase of sensitivity of the Colr forms is connected with structural changes within bacterial cell wall which is the target for complement as well as for colistine.
比较了大肠杆菌K1、肠炎沙门氏菌、鼠伤寒沙门氏菌菌株及其对黏菌素耐药的适应性形式（Colr形式）对正常脐带血清和正常牛血清杀菌作用的敏感性。结果表明，与初始菌株相比，Colr形式对血清更敏感。Colr形式敏感性的增加与细菌细胞壁内的结构变化有关，细菌细胞壁是补体和黏菌素的作用靶点。
