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低体重儿(1000克及以下)的发病率和死亡率(作者译)

[Morbidity and mortality in low-birth-weight infants (1,000 g, or less (author's transl)].

作者信息

Lozano Giménez C, Sanromán Martínez L, Miranda Segovia F

出版信息

An Esp Pediatr. 1976 Sep-Oct;9(5):462-8.

PMID:999093
Abstract

50 low-birth-weight infants (1,000 g. or less) admitted to an Intensive Care Unit from January 1972 up to December 1974 are evaluated. Obstetrical data maturity and morbidity are compared in order to investigate factors that might predispose survival of these infants. Significant differences in gestational age, birth weight and maturity have been encountered. Mortality rate increases with a low Apgar score at one and five minutes, a low hematocrit an admission, early appearance of apnea, respiratory distress, when ressuscitation was required, need for assisted ventilation and septicemia. Among the factors that improve the rate of survival are: being small for gestational age, early rupture of membranes and temperature on admission above 35.5 degrees (axillary). Problems most frequently encountered were respiratory distress, apnea, infection and metabolic disturbances. Mortality rate was 76%, lowered to 50% among the small for gestational age group. The main causes of death were sepsis, severe hypoxia and intracraneal hemorrhage.

摘要

对1972年1月至1974年12月期间入住重症监护病房的50名低体重婴儿(1000克及以下)进行了评估。比较了产科数据、成熟度和发病率,以调查可能影响这些婴儿存活的因素。研究发现胎龄、出生体重和成熟度存在显著差异。死亡率随着1分钟和5分钟时阿氏评分低、入院时血细胞比容低、呼吸暂停和呼吸窘迫的早期出现、需要复苏、需要辅助通气以及败血症而增加。提高存活率的因素包括:小于胎龄、胎膜早破和入院时体温高于35.5度(腋温)。最常遇到的问题是呼吸窘迫、呼吸暂停、感染和代谢紊乱。死亡率为76%,小于胎龄组的死亡率降至50%。主要死亡原因是败血症、严重缺氧和颅内出血。

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