[林可霉素对细胞培养的作用]
[Effect of lincomycin on a cell culture].
作者信息
Iakimenko L N, Znamenskaia T M, Golubchik I S
出版信息
Antibiotiki. 1976 Oct;21(10):902-4.
PMID:999238
Abstract
Cumulative and toxic properties of lincomycin evident from increased numbers of pathological mitosis were found on three-fold treatment of various cell lines with the antibiotic in concentrations of 100 or 200 Units/ml for 1.5 years. The toxicity level was not high since the other indices of the mitotic regimen remained unchanged.
摘要
在用浓度为100或200单位/毫升的抗生素对各种细胞系进行三倍剂量处理1.5年后，发现林可霉素的累积和毒性特性表现为病理性有丝分裂数量增加。由于有丝分裂方案的其他指标保持不变，毒性水平并不高。
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