Markina S S, Favorova L A, Solodovnikova A V, Lineva I N, Polikarpova L K
Zh Mikrobiol Epidemiol Immunobiol. 1978 Jul(7):52-6.
Corynephage distribution was studied in the nasopharyngeal washings of 252 persons infected with C. diphtheriae of gravis type, toxigenic (21 patients and 147 carriers) and non-toxigenic ones (84 carriers), and in 468 uninfected persons in collective bodies under different epidemic conditions. Corynephages were isolated from the nasopharyngeal washings only in persons infected with toxigenic C. diphtheriae--in 4 (of 21) patients, and in 21% (of 147) carriers. Phages tox+ (4--6.2%) were revealed only in carriers of toxigenic C. diphtheriae with numerous bacteria in the nasopharynx and in diphtheria patients. Carriers of nontoxigenic diphtheria bacilli can become infected with phage tox+ only together with the toxigenic strains (reinfection). The data obtained indicated that toxigenic and nontoxigenic C. diphtheriae strains were individual variants.
研究了252例感染重型产毒白喉棒状杆菌(21例患者和147例带菌者)和非产毒白喉棒状杆菌(84例带菌者)的人的鼻咽冲洗液中的棒状噬菌体分布情况,并研究了不同流行条件下集体单位中468例未感染者的鼻咽冲洗液中的棒状噬菌体分布情况。仅在感染产毒白喉棒状杆菌的人中从鼻咽冲洗液中分离出棒状噬菌体——21例患者中有4例,147例带菌者中有21%。仅在鼻咽部有大量细菌的产毒白喉棒状杆菌带菌者和白喉患者中发现了tox+噬菌体(4 - 6.2%)。非产毒白喉杆菌带菌者只有与产毒菌株一起(再感染)才会感染tox+噬菌体。所获得的数据表明,产毒和非产毒白喉棒状杆菌菌株是个体变体。