Oberklaid F, Hopkins I J
Arch Dis Child. 1976 Sep;51(9):719-21. doi: 10.1136/adc.51.9.719.
A previously well infant developed severe muscle weakness and hypotonia at 6 months of age. This was reversed by anticholinesterase medication. However, she had subsequent further weakness and died at 10 months after an acute respiratory arrest. The clinical pattern was that of the 'juvenile' form of myasthenia gravis rather than the 'congenital' forms which have previously been described in early infancy.
一名此前健康的婴儿在6个月大时出现了严重的肌肉无力和肌张力减退。抗胆碱酯酶药物治疗使其症状得到缓解。然而,她随后又出现了进一步的肌无力,并在急性呼吸骤停后10个月死亡。临床症状表现为重症肌无力的“青少年”型,而非先前在婴儿早期所描述的“先天性”类型。