在二甲基亚砜中液氮保存的静脉移植物的长期通畅性。

Weber T R, Lindenauer S M, Dent T L, Allen E, Salles C A, Weatherbee L

Ann Surg. 1976 Dec;184(6):709-12. doi: 10.1097/00000658-197612000-00008.

Autogenous canine jugular veins were stored in 15% dimethyl sulfoxide (DMSO) in liquid nitrogen vapor for one to 28 days and then implanted in the carotid artery as autografts. The patency rate at one year was 62.5-87.5%. The patency rate of fresh jugular vein autografts placed in the carotid artery for one year was 75%. Similar autografts stored in liquid nitrogen vapor for one to 28 days without the cryopreservative DMSO exhibited a zero to 12.5% patency rate at one year. Scanning electron microscope studies revealed preservation of theendothelium in DMSO protected veins and a damaged or sloughed endothelium in veins frozen without DMSO cryopreservation.

将自体犬颈静脉置于含15%二甲基亚砜（DMSO）的液氮蒸汽中保存1至28天，然后作为自体移植物植入颈动脉。一年时的通畅率为62.5%至87.5%。新鲜颈静脉自体移植物植入颈动脉一年的通畅率为75%。在不含冷冻保护剂DMSO的情况下于液氮蒸汽中保存1至28天的类似自体移植物，一年时的通畅率为0至12.5%。扫描电子显微镜研究显示，DMSO保护的静脉中内皮得以保存，而未进行DMSO冷冻保存的冷冻静脉中内皮受损或脱落。