Ragheb M I, Ramadan A A, Khalil M A
Ann Thorac Surg. 1976 Nov;22(5):483-9. doi: 10.1016/s0003-4975(10)64458-x.
Amebic infection is endemic in tropical and subtropical countries and still remains a common cause of chronic morbidity in these areas. This is a report of 10 patients with different intrathoracic presentations of amebic liver abscess who were treated surgically after conservative measures had failed. Five of these patients had empyema when first seen, 3 had lung abscess, and 1 had intrathoracic shadow that proved on exploration to be an amebic liver abscess. All of these 9 patients had abscesses on the right side secondary to amebic liver abscess of the right lobe of the liver. The tenth patient had amebic pericarditis secondary to amebic abscess of the left lobe of the liver. Failure of conservative treatment in these patients is attributed to the thick nature of the amebic pus and the severe reaction of the pleura and pericardium to the amebic infection. To avoid the serious complication of pleuropulmonary amebiasis, early operation is advised for large liver abscesses that are unlikely to be controlled by conservative treatment. Transpleural drainage of such abscesses gives direct approach to their sites, which are commonly located in the superior part of the right lobe of the liver. Such drainage has proved to be safe provided that the patient is receiving antiamebic drug treatment.
阿米巴感染在热带和亚热带国家呈地方性流行,在这些地区仍然是慢性发病的常见原因。本文报告了10例阿米巴肝脓肿有不同胸内表现的患者,他们在保守治疗失败后接受了手术治疗。其中5例患者初诊时患有脓胸,3例患有肺脓肿,1例胸腔内阴影经探查证实为阿米巴肝脓肿。这9例患者均因肝右叶阿米巴肝脓肿继发右侧脓肿。第10例患者因肝左叶阿米巴脓肿继发阿米巴心包炎。这些患者保守治疗失败归因于阿米巴脓液质地浓稠以及胸膜和心包对阿米巴感染的严重反应。为避免胸膜肺阿米巴病的严重并发症,对于不太可能通过保守治疗控制的大肝脓肿,建议早期手术。此类脓肿经胸膜引流可直接到达其通常位于肝右叶上部的部位。只要患者接受抗阿米巴药物治疗,这种引流已被证明是安全的。