2-硝基-5-硫氰基苯甲酸与巯基反应中的替代产物。
Alternative products in the reaction of 2-nitro-5-thiocyanatobenzoic acid with thiol groups.
作者信息
Price N C
出版信息
Biochem J. 1976 Oct 1;159(1):177-80. doi: 10.1042/bj1590177.
Abstract
2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives. Evidence was obtained for formation of both the S-cyano derivative and the mixed disulphide derivative. Formation of the S-cyano derivative can be promoted by addition of excess of CN-to the reaction mixture.
摘要
2-硝基-5-硫氰基苯甲酸已被提议作为一种将蛋白质中的巯基转化为其S-氰基衍生物的试剂。已获得形成S-氰基衍生物和混合二硫键衍生物的证据。通过向反应混合物中加入过量的CN-可以促进S-氰基衍生物的形成。
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