Tsakok F H, Koh S, Ratnam S S
Br Med J. 1976 Dec 18;2(6050):1481-4. doi: 10.1136/bmj.2.6050.1481.
Tests of coagulation, fibrinolysis, and platelet function were performed in 17 patients with intact molar pregnancies. Women with intact molar pregnancies had higher fibrinogen factor VIII, and fibrinogen degradation products, concentrations and lower prothrombin, factor X, plasminogen, and plasminogen activator concentrations than controls with normal pregnancies. They also had reduced platelet counts and thromboelastographic values, which indicated hypocoagulability. These results suggest that intravascular coagulation occurs in intact hydatidiform molar pregnancies.
对17例完全性葡萄胎妊娠患者进行了凝血、纤维蛋白溶解和血小板功能检测。与正常妊娠对照组相比，完全性葡萄胎妊娠女性的纤维蛋白原、凝血因子VIII和纤维蛋白原降解产物浓度更高，而凝血酶原、凝血因子X、纤溶酶原和纤溶酶原激活剂浓度更低。她们的血小板计数和血栓弹力图值也降低，提示凝血功能低下。这些结果表明，完全性葡萄胎妊娠中发生了血管内凝血。
