完全性葡萄胎妊娠中的凝血与纤溶
Coagulation and fibrinolysis in intact hydatidiform molar pregnancy.
作者信息
Tsakok F H, Koh S, Ratnam S S
出版信息
Br Med J. 1976 Dec 18;2(6050):1481-4. doi: 10.1136/bmj.2.6050.1481.
Abstract
Tests of coagulation, fibrinolysis, and platelet function were performed in 17 patients with intact molar pregnancies. Women with intact molar pregnancies had higher fibrinogen factor VIII, and fibrinogen degradation products, concentrations and lower prothrombin, factor X, plasminogen, and plasminogen activator concentrations than controls with normal pregnancies. They also had reduced platelet counts and thromboelastographic values, which indicated hypocoagulability. These results suggest that intravascular coagulation occurs in intact hydatidiform molar pregnancies.
摘要
对17例完全性葡萄胎妊娠患者进行了凝血、纤维蛋白溶解和血小板功能检测。与正常妊娠对照组相比，完全性葡萄胎妊娠女性的纤维蛋白原、凝血因子VIII和纤维蛋白原降解产物浓度更高，而凝血酶原、凝血因子X、纤溶酶原和纤溶酶原激活剂浓度更低。她们的血小板计数和血栓弹力图值也降低，提示凝血功能低下。这些结果表明，完全性葡萄胎妊娠中发生了血管内凝血。
相似文献
1
Coagulation and fibrinolysis in intact hydatidiform molar pregnancy.完全性葡萄胎妊娠中的凝血与纤溶
Br Med J. 1976 Dec 18;2(6050):1481-4. doi: 10.1136/bmj.2.6050.1481.
2
Coagulation and fibrinolysis in molar pregnancy.葡萄胎中的凝血与纤维蛋白溶解
Am J Obstet Gynecol. 1977 Apr 15;127(8):855-60. doi: 10.1016/0002-9378(77)90118-1.
3
Plasminogen activator inhibitors (PAI-1 and PAI-2) in normal pregnancies, pre-eclampsia and hydatidiform mole.
Br J Obstet Gynaecol. 1993 Apr;100(4):370-4. doi: 10.1111/j.1471-0528.1993.tb12982.x.
4
Review on coagulation in trophoblastic disease.滋养细胞疾病中的凝血综述。
Ann Acad Med Singap. 1982 Oct;11(4):555-60.
5
Maternal plasma testosterone levels in molar pregnancy.葡萄胎妊娠时母体血浆睾酮水平。
Br J Obstet Gynaecol. 1977 Jul;84(7):528-30. doi: 10.1111/j.1471-0528.1977.tb12639.x.
6
[Serum and tissue 17 beta hydroxysteroid dehydrogenase and estrogens in hydatidiform mole].
J Clin Chem Clin Biochem. 1983 Feb;21(2):77-82.
7
Decreased aggregability of platelets in hydatidiform molar pregnancy.葡萄胎妊娠中血小板聚集性降低。
Thromb Res. 1988 Oct 1;52(1):75-6. doi: 10.1016/0049-3848(88)90044-8.
8
Effect of hydatidiform molar vesicular fluid on blood coagulation.葡萄胎水泡液对血液凝固的影响。
Am J Obstet Gynecol. 1985 Nov 15;153(6):703-7. doi: 10.1016/s0002-9378(85)80263-5.
9
Serum free estriol and estriol glucuronide fractions in hydatidiform mole measured by radioimmunoassay.用放射免疫分析法测定葡萄胎患者血清中游离雌三醇和雌三醇葡萄糖醛酸苷组分。
Obstet Gynecol. 1977 Mar;49(3):303-7.
10
Plasma 19-hydroxyandrostenedione and androstenedione levels in hydatidiform moles and early pregnancies with and without hypertensive diseases.葡萄胎以及合并或未合并高血压疾病的早期妊娠中血浆19-羟雄烯二酮和雄烯二酮水平
Aust N Z J Obstet Gynaecol. 1989 Aug;29(3 Pt 1):238-41. doi: 10.1111/j.1479-828x.1989.tb01727.x.
引用本文的文献
1
Complete blood count parameters may have a role in diagnosis of gestational trophoblastic disease.全血细胞计数参数可能在妊娠滋养细胞疾病的诊断中发挥作用。
Pak J Med Sci. 2015;31(3):667-71. doi: 10.12669/pjms.313.7109.
2
Abnormal expression of plasminogen activator inhibitors in patients with gestational trophoblastic disease.妊娠滋养细胞疾病患者纤溶酶原激活物抑制剂的异常表达。
Am J Pathol. 1996 Oct;149(4):1229-39.
3
Coagulation problems in human pregnancy.人类妊娠中的凝血问题。
Postgrad Med J. 1979 May;55(643):367-71. doi: 10.1136/pgmj.55.643.367.
本文引用的文献
1
THE FIBRINOLYTIC SYSTEM IN BLOOD AFTER RETENTION OF A DEAD FETUS AND DURING NORMAL LABOR.死胎滞留后及正常分娩期间血液中的纤溶系统
Am J Obstet Gynecol. 1965 May 15;92:221-6. doi: 10.1016/s0002-9378(65)80011-4.
2
THE AGGREGATION OF BLOOD PLATELETS.血小板的聚集
J Physiol. 1963 Aug;168(1):178-95. doi: 10.1113/jphysiol.1963.sp007185.
3
The mechanism of clot dissolution by plasmin.纤溶酶溶解血栓的机制。
J Clin Invest. 1959 Jul;38(7):1086-95. doi: 10.1172/JCI103885.
4
Disseminated intravascular coagulation: a cause of shock.弥散性血管内凝血：休克的一个原因。
Ann Surg. 1959 Apr;149(4):462-70. doi: 10.1097/00000658-195904000-00002.
5
The pathologic anatomy of eclampsia, bilateral renal cortical necrosis, pituitary necrosis, and other acute fatal complications of pregnancy, and its possible relationship to the generalized Shwartzman phenomenon.子痫、双侧肾皮质坏死、垂体坏死及其他妊娠急性致命并发症的病理解剖，及其与全身性施瓦茨曼现象的可能关系。
Am J Obstet Gynecol. 1953 Sep;66(3):507-39. doi: 10.1016/0002-9378(53)90068-4.
6
Determination of alpha-2-macroglobulin as trypsin-protein esterase.将α-2-巨球蛋白测定为胰蛋白酶-蛋白质酯酶。
Clin Chim Acta. 1966 Oct;14(4):493-501. doi: 10.1016/0009-8981(66)90037-4.
7
8
Thrombo-embolism and increased platelet adhesiveness in post-splenectomy thrombocytosis.
Australas Ann Med. 1966 May;15(2):122-8. doi: 10.1111/imj.1966.15.2.122.
9
Fibrinolytic enzyme system and pregnancy.纤溶酶系统与妊娠
Br Med J. 1969 Aug 16;3(5667):387-9. doi: 10.1136/bmj.3.5667.387.
10
Antithrombin 3, antifactor Xa and heparin.抗凝血酶3、抗Xa因子与肝素。
Br J Haematol. 1970 Sep;19(3):283-305. doi: 10.1111/j.1365-2141.1970.tb01627.x.
Zotero 插件