Benezech M, Bourgeois M
Encephale. 1976;2(4):305-15.
This is an attempt to describe a common syndrom of polygonosomy. Medical, psychological and social incidences of XXX, XXY, XYY, genotypes indicate that these chromosomal aberrations share identical features: phenotypic abnormalities (high stature, dermatoglyphes abnormalities), neuropsychic troubles (neurological symptoms and mental fragility) and antisocial tendancy. One can suppose that at least some polygonosomic persons have a minimal brain dysfunction (or damage), which causes more vulnerability to environnement, deprivation and stress. Relational, educational and socio-economical factors appear now to have a marked role in the etiopathogenesis of these psychiatric troubles. Some forensic and ethical problems of human genetic research are reviewed, such as the so-called "criminal chromosome", supplementary Y chromosome, a myth based upon false and premature scientific assertions.
这是一次描述多体综合征常见症状的尝试。XXX、XXY、XYY基因型的医学、心理及社会发生率表明，这些染色体畸变具有相同特征：表型异常（身材高大、皮纹异常）、神经精神问题（神经症状及精神脆弱）及反社会倾向。可以推测，至少部分多体综合征患者存在轻微的脑功能障碍（或损伤），这使得他们更容易受到环境、贫困及压力的影响。关系、教育及社会经济因素目前似乎在这些精神问题的病因学中起着显著作用。本文回顾了人类基因研究中的一些法医及伦理问题，比如所谓的“犯罪染色体”，即额外的Y染色体，这是一个基于错误和过早科学论断的神话。
