Pleshkova S M, Tsvetkova T V
Biull Eksp Biol Med. 1978 Sep;86(9):347-9.
The influence of common allergic response of delayed type to brucellosis antigen on the processes of glycolysis and dehydrogenase activity of Krebs' cycle in guinea pigs' blood and organs was studied. Along with inhibitory activity of four dehydrogenases investigated there was a depression of the glucolysis processes connected with reduction of the lactate, pyruvate content, and with depression of the LDH activity. An increase of the anaerobic fractions and lowering of aerobic fractions content and of the spectrum excess was seen in the isoenzyme LDH spectrum.
研究了豚鼠血液和器官中布鲁氏菌病抗原迟发型常见过敏反应对糖酵解过程及三羧酸循环脱氢酶活性的影响。在所研究的四种脱氢酶的抑制活性之外,还存在与乳酸、丙酮酸含量降低以及乳酸脱氢酶(LDH)活性降低相关的糖酵解过程抑制。在LDH同工酶谱中可见厌氧组分增加,需氧组分含量及光谱过量降低。