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X射线照射后伯基特淋巴瘤细胞的恢复情况。

Recovery in Burkitt lymphoma cells after X-ray irradiation.

作者信息

Inada T, Kasuga T, Nojiri I, Furuse T, Hiraoka T

出版信息

Gan. 1976 Jun;67(3):451-3.

PMID:1001870
Abstract

The radiation response of cultured Burkitt lymphoma cell, known as a particular cell line of high radiosensitivity, was studied by the colony formation method. The values of n, Dq, and Do derived from the survival curve after a single dose X-irradiation resulted in small values as 1.1, 10 rad, and 125 rad. The maximum recovery of about 5% was observed 3 hr after the irradiation by a split-dose experiment. In the survival curve derived from a split-dose irradiation, n and Dq increased while Do remained unchanged. The reason for these increases in n and Dq may be attributed to the nonhomogeneous or mixed population response.

摘要

通过集落形成法研究了培养的伯基特淋巴瘤细胞(一种已知具有高放射敏感性的特定细胞系)的辐射反应。单次剂量X射线照射后,从存活曲线得出的n、Dq和Do值较小,分别为1.1、10拉德和125拉德。通过分次剂量实验,在照射后3小时观察到约5%的最大恢复率。在分次剂量照射得出的存活曲线中,n和Dq增加,而Do保持不变。n和Dq增加的原因可能归因于非均匀或混合群体反应。

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