Sherman A, Bini E J
Division of Gastroenterology, New York University Medical Center and Department of Veterans Affairs Medical Center, New York 10010, USA.
Am J Gastroenterol. 1999 Feb;94(2):511-3. doi: 10.1111/j.1572-0241.1999.886_o.x.
Pill-induced esophageal injury is a well described clinical entity. In contrast, pill-induced gastric injury has not been well characterized. In this report, we describe two patients with acute gastric ulcers due to pill ingestion and review the available literature on pill-induced gastric injury. The first patient presented with upper gastrointestinal hemorrhage and was found to have a large gastric ulcer with multiple potassium chloride pills in the ulcer crater. The second patient presented with odynophagia and endoscopy revealed doxycycline-induced esophageal and gastric injury. To our knowledge, this is the first case report of doxycycline-induced gastric ulcer.
药物性食管损伤是一种已被充分描述的临床病症。相比之下，药物性胃损伤尚未得到很好的界定。在本报告中，我们描述了两名因吞服药物而导致急性胃溃疡的患者，并回顾了关于药物性胃损伤的现有文献。首例患者出现上消化道出血，经检查发现有一个大的胃溃疡且溃疡灶内有多个氯化钾药丸。第二例患者出现吞咽痛，内镜检查显示有强力霉素所致的食管和胃损伤。据我们所知，这是首例关于强力霉素所致胃溃疡的病例报告。
