The efficacy of CNES-2 in detecting the neurobehavioral changes of epileptic patients.

The Neurobehavioral Evaluation System (NES) and the Chinese Neurobehavioral Evaluation System-2 (CNES-2) have been widely used to detect central nervous dysfunction associated with exposure to a variety of neurotoxicants. The NES has recently been validated as a measure of central nervous system (CNS) dysfunction in patients with well-characterized neurological disorders such as Parkinson disease and multiple sclerosis. Validation of the NES was also been done through correlation study with traditional neuropsychological tests. The purpose of present study was to assess the efficacy of CNES-2 in detecting the neurobehavioral change of the epileptic patients, another neurological disorders that can have associated subtle neurobehavioral changes. Furthermore, seizures sometimes occur following exposure to neurotoxicants. Results showed the performance on many subtests of CNES-2 was impaired in the epileptic patients compared to the controls. Our conclusion is that the CNES-2 is a worthwhile tool for identifying subtle neurobehavioral abnormalities.