Liguori R, Rizzi R, Vetrugno R, Salvi F, Lugaresi A, Cevoli S, Montagna P
Institute of Neurology, University of Bologna, Italy.
Muscle Nerve. 1999 Feb;22(2):262-5. doi: 10.1002/(sici)1097-4598(199902)22:2<262::aid-mus16>3.0.co;2-1.
We describe 2 patients with associated central and peripheral demyelination. Electrophysiological studies revealed a demyelinating polyneuropathy with sensory and motor conduction blocks. Visual evoked potentials were abnormal. Motor evoked potentials showed abnormal central conduction time in 1 patient. Magnetic resonance imaging revealed regions of abnormal high signal in the spinal cord and brain; sural nerve biopsy disclosed a demyelinating neuropathy. Both patients showed clinical and electrophysiological improvement after steroid therapy.
