Mizoue T, Ueda R, Tokui N, Hino Y, Yoshimura T
Department of Clinical Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan.
Int J Epidemiol. 1998 Dec;27(6):984-8. doi: 10.1093/ije/27.6.984.
Although smoking cessation is strongly associated with subsequent weight gain, it is not clear whether the initial gain in weight after smoking cessation remains over time.
Cross-sectional analyses were made, using data from periodic health examinations for workers, on the relationship between body mass index (BMI) and the length of smoking cessation. In addition, linear regression coefficients of BMI on the length of cessation were estimated according to alcohol intake and sport activity, to examine the modifying effect of these factors on the weight of former smokers.
Means of BMI were 23.1 kg/m2, 23.3 kg/m2, 23.6 kg/m2 for light/medium smokers, heavy smokers and never smokers, respectively. Among former smokers who had smoked > or = 25 cigarettes a day, odds ratio (OR) of BMI >25 kg/m2 were 1.88 (95% confidence interval [CI] : 1.05-3.35), 1.32 (95% CI : 0.74-2.34), 0.66 (95% CI: 0.33-1.31) for those with 2-4 years, 5-7 years, and 8-10 years of smoking cessation, respectively. The corresponding OR among those who previously consumed <25 cigarettes a day were 1.06 (95% CI: 0.58-1.94), 1.00 (95% CI: 0.58-1.71), and 1.49 (95% CI: 0.95-2.32).
The results suggest that although heavy smokers may experience large weight gain and weigh more than never smokers in the few years after smoking cessation, they thereafter lose weight to the never smoker level, while light and moderate smokers gain weight up to the never smoker level without any excess after smoking cessation.
尽管戒烟与随后的体重增加密切相关，但尚不清楚戒烟后最初的体重增加是否会随时间持续存在。
利用工人定期健康检查的数据进行横断面分析，研究体重指数（BMI）与戒烟时长之间的关系。此外，根据饮酒量和体育活动情况估计BMI关于戒烟时长的线性回归系数，以检验这些因素对既往吸烟者体重的修正作用。
轻度/中度吸烟者、重度吸烟者和从不吸烟者的BMI均值分别为23.1kg/m²、23.3kg/m²、23.6kg/m²。在既往每天吸烟≥25支的既往吸烟者中，戒烟2 - 4年、5 - 7年和8 - 10年者BMI＞25kg/m²的比值比（OR）分别为1.88（95%置信区间[CI]：1.05 - 3.35）、1.32（95%CI：0.74 - 2.34）、0.66（95%CI：0.33 - 1.31）。在既往每天吸烟＜25支的人群中，相应的OR分别为1.06（95%CI：0.58 - 1.94）、1.00（95%CI：0.58 - 1.71）和1.49（95%CI：0.95 - 2.32）。
结果表明，尽管重度吸烟者在戒烟后的几年内可能会出现大幅体重增加且体重高于从不吸烟者，但之后他们的体重会降至从不吸烟者的水平，而轻度和中度吸烟者在戒烟后体重会增加至从不吸烟者的水平且不会有任何超重。
