Ozgen A, Akata D, Arat A, Ozdogan M, Akhan O, Ozmen M N
Department of Radiology, Hacettepe University School of Medicine, Sihhiye, 06100, Ankara, Turkey.
Abdom Imaging. 1999 Mar-Apr;24(2):188-90. doi: 10.1007/s002619900473.
A small, fibrotic, and even calcified spleen is the hallmark of homozygote sickle cell disease in adults. Such a condition is very rare in sickle-thalassemia and, to our knowledge, not previously reported in a sickle cell trait. We report two heterozygote sickle cell siblings with splenic calcifications, one sickle cell trait and one sickle-beta+-thalassemia, without any history suggestive of splenic vasooclusive-infarctive crisis.
小的、纤维化甚至钙化的脾脏是成人纯合子镰状细胞病的标志。这种情况在镰状细胞-地中海贫血中非常罕见，据我们所知，以前在镰状细胞性状中未见报道。我们报告了两名患有脾钙化的杂合子镰状细胞病患者，一名为镰状细胞性状，另一名为镰状-β+地中海贫血，均无提示脾血管阻塞性梗死危象的病史。
