酵母中的磷脂酶

Phospholipases in yeast.

作者信息

Torgler CN, Meldrum E

机构信息

Geneva Biomedical Research Institute, Chemin des Aulx 14, 1228 Plan-les-Ouates, Geneva, Switzerland

出版信息

Semin Cell Dev Biol. 1997 Jun;8(3):333-338. doi: 10.1006/scdb.1997.0155.

DOI:10.1006/scdb.1997.0155

PMID:10024497

Abstract

The central role that different phospholipases play in many signal transduction pathways has been intensively studied by classical biochemical and molecular approaches. One approach not extensively pursued, has been the use of yeast as a model system for functional analysis of different aspects of phospholipase signalling. This review concentrates on attempts to establish yeast in this role and aims to demonstrate the potential offered by this approach.

摘要

不同磷脂酶在许多信号转导途径中所起的核心作用，已通过经典的生化和分子方法得到深入研究。一种未被广泛采用的方法是，利用酵母作为模型系统，对磷脂酶信号传导的不同方面进行功能分析。本综述着重介绍了为使酵母发挥这一作用所做的尝试，并旨在展示这种方法所具有的潜力。