Lowe Thomas G, Alongi Paul R, Smith David A B, O'Brien Michael F, Mitchell Shari L, Pinteric Raymarla J
Woodridge Orthopaedic and Spine Center, Wheat Ridge, Colorado, USA.
Spine (Phila Pa 1976). 2003 Oct 1;28(19):2232-41; discussion 2241-2. doi: 10.1097/01.BRS.0000085028.70985.39.
A radiographic and clinical outcomes analysis of 41 patients treated for thoracolumbar adolescent idiopathic scoliosis utilizing a single anterior rigid rod construct.
To evaluate the necessity of structural interbody support to improve primary curve correction and preserve or augment lordosis when used in conjunction with a single anterior rigid rod construct, to identify parameters that predict horizontalization of the lowest instrumented vertebra, adjacent disc angulation, and distal uninstrumented vertebrae, and to assess patient satisfaction following surgery.
Instrumentation-induced kyphosis has been a concern with nonrigid anterior systems used in the past for the treatment of scoliosis. Interbody structural support has been recommended to maintain appropriate sagittal profile when anterior systems are utilized. It has also been suggested that the use of structural interbody support creates a fulcrum to increase curve correction when compression is applied to the convexity of the deformity. However, the necessity of interbody structural support when used in conjunction with a rigid anterior system has not been previously evaluated in patients with adolescent idiopathic scoliosis.
Forty-one patients mean age 15.9 years (range 12.1-18.6 years) with thoracolumbar adolescent idiopathic scoliosis underwent anterior spinal fusion using a single 6.0 to 6.5 mm solid rod construct between June 1995 and August 1999 performed by the senior author (T.G.L.). Four additional patients with thoracolumbar curves with similar anterior instrumentation over the same time period were lost to follow-up or had incomplete records and were not included in the study. Structural interbody support was used in 21 patients and packed morselized autograft alone was used in 20 patients. The patients in the group with packed morselized bone alone generally underwent surgery earlier in the series before the author began using structural interbody support on a regular basis. Each patient had a minimum follow-up of 3 years. Preoperative, initial, and most recent (>3 years) follow-up radiographs were reviewed to determine in each group Cobb angle measurements, flexibility of primary, secondary, and fractional curves, apical and end vertebral translation, lowest instrumented vertebral and caudal disc angulation, global coronal and sagittal balance, and sagittal Cobb measurements in both instrumented levels as well as lumbar lordosis (T12-S1). In addition, the SRS outcomes instrument was completed by 38 of 41 patients.
The mean preoperative primary curve in patients with structural support was 47 degrees (Group II) and 45 degrees in patients without structural support (Group I). Mean curve correction was to 13 degrees in Groups I and II. One patient in Group II became slightly more unbalanced at final follow-up; otherwise all were improved after surgery. Sagittal measurements over instrumented segments as well as total lumbar lordosis (T12-S1) was maintained between preoperative and final postoperative values in both groups. Similarly, in both groups, when horizontalization of the distal end instrumented vertebra was achieved on the preoperative reverse side-bending radiograph, more normal relationships were achieved between instrumented and distal noninstrumented segments (adjacent disc angulation and fractional lumbar curve) at final follow-up (P <or= 0.01). Patients in both groups were equally pleased with their clinical outcomes based on the SRS outcomes instrument.
The use of interbody structural support does not appear to be necessary to maintain an appropriate sagittal profile or to maximize coronal curve correction when a rigid rod construct with packed morselized bone is used for the treatment of thoracolumbar adolescent idiopathic scoliosis. Parameters predicting horizontalization of the lower instrumented vertebra and uninstrumented segments below the construct were identified, which, if achieved, should predict an optimal long-term outcome. Clinical outcomes were very good in both groups.
对41例采用单一前路刚性棒结构治疗胸腰段青少年特发性脊柱侧凸患者的影像学和临床结果进行分析。
评估在与单一前路刚性棒结构联合使用时,结构性椎间支撑对于改善主弯矫正以及维持或增加前凸的必要性;确定预测最低固定椎体水平化、相邻椎间盘成角以及远端未固定椎体的参数;并评估患者术后满意度。
器械诱导性后凸一直是过去用于治疗脊柱侧凸的非刚性前路系统所关注的问题。当采用前路系统时,推荐使用椎间结构性支撑以维持合适的矢状面形态。也有人提出,当对畸形凸侧施加压缩力时,使用结构性椎间支撑可形成一个支点以增加弯度矫正。然而,在青少年特发性脊柱侧凸患者中,与刚性前路系统联合使用时椎间结构性支撑的必要性此前尚未得到评估。
1995年6月至1999年8月期间,41例平均年龄15.9岁(范围12.1 - 18.6岁)的胸腰段青少年特发性脊柱侧凸患者由资深作者(T.G.L.)采用单一6.0至6.5mm实心棒结构进行了前路脊柱融合术。同期另外4例具有类似前路器械固定的胸腰段侧弯患者失访或记录不完整,未纳入本研究。21例患者使用了结构性椎间支撑,20例患者仅使用了碎骨块自体骨填充。仅使用碎骨块骨的组中的患者通常在作者开始常规使用结构性椎间支撑之前就较早地接受了手术。每位患者的随访时间至少为3年。回顾术前、初始及最近(>3年)随访的X线片,以确定每组的Cobb角测量值、主弯、次弯及分节段弯度的柔韧性、顶椎和终椎移位、最低固定椎体和尾侧椎间盘成角、整体冠状面和矢状面平衡以及两个固定节段的矢状面Cobb测量值以及腰椎前凸(T12 - S1)。此外,41例患者中的38例完成了脊柱侧凸研究学会(SRS)的结果评估工具。
使用结构性支撑的患者术前主弯平均为47度(II组),未使用结构性支撑的患者为45度(I组)。I组和II组的平均弯度矫正均为13度。II组中有1例患者在最终随访时变得稍微更加失衡;除此之外,所有患者术后均有改善。两组在术前和术后最终值之间均维持了固定节段的矢状面测量值以及总的腰椎前凸(T12 - S1)。同样,在两组中,当术前反向侧弯X线片上实现了远端固定椎体的水平化时,在最终随访时固定节段与远端未固定节段之间(相邻椎间盘成角和分节段腰椎弯度)达到了更正常的关系(P≤0.01)。基于SRS结果评估工具,两组患者对其临床结果同样满意。
当使用带有碎骨块骨填充的刚性棒结构治疗胸腰段青少年特发性脊柱侧凸时,使用椎间结构性支撑对于维持合适的矢状面形态或最大化冠状面弯度矫正似乎并非必要。确定了预测较低固定椎体和结构下方未固定节段水平化的参数,如果实现这些参数,则应能预测最佳的长期结果。两组的临床结果均非常好。