Bennett J L, Pelak V A, Mourelatos Z, Bird S, Galetta S L
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, USA.
Surv Ophthalmol. 1999 Jan-Feb;43(4):341-4. doi: 10.1016/s0039-6257(98)00047-2.
A tonic pupil may occur in isolation or as part of a systemic disorder. We report a patient who developed tonic pupils and an abduction deficit in the setting of polyarteritis nodosa. The combination of a tonic pupil and an abduction deficit should suggest the possibility of a vasculopathic disorder, because the ciliary ganglion and lateral rectus muscle are both supplied by the lateral muscular artery. Widespread small artery and arteriolar narrowing and occlusion are the hallmarks of polyarteritis nodosa. Unusual ischemic syndromes may occur, such as this rare combination of neuro-ophthalmic signs, by involvement of both the nutrient artery and its collaterals. We are unaware of other reports of neuropathic tonic pupils in association with polyarteritis nodosa.
强直性瞳孔可单独出现,也可作为全身性疾病的一部分出现。我们报告了一名在结节性多动脉炎背景下出现强直性瞳孔和外展功能障碍的患者。强直性瞳孔和外展功能障碍同时出现应提示血管病变性疾病的可能性,因为睫状神经节和外直肌均由眼外肌动脉供血。广泛的小动脉和小动脉狭窄及闭塞是结节性多动脉炎的特征。由于营养动脉及其侧支均受累,可能会出现不寻常的缺血综合征,如这种罕见的神经眼科体征组合。我们未发现其他关于结节性多动脉炎伴神经性强直性瞳孔的报告。