多灶性部分性癫痫中伴有血管生成异常和慢性炎症的皮质发育异常

Cortical dysplasia with angiodysgenesis and chronic inflammation in multifocal partial epilepsy.

作者信息

Thom M, Moran N F, Plant G T, Stevens J M, Scaravilli F

机构信息

Department of Neuropathology, The National Hospital for Neurology and Neurosurgery, London, UK.

出版信息

Neurology. 1999 Feb;52(3):654-7. doi: 10.1212/wnl.52.3.654.

DOI:10.1212/wnl.52.3.654

PMID:10025810

Abstract

A 25-year-old man with a long history of temporal lobe epilepsy developed right occipital lobe seizures and a progressive right homonymous hemianopia. MRI showed diffuse enhancement of the left temporoparieto-occipital white matter and cortical thickening of the left medial temporal lobe. The resected temporal lobe revealed cortical dysplasia and angiodysplasia with foci of more recent ischemic necrosis and chronic inflammation as an explanation for the clinical deterioration.

摘要

一名有长期颞叶癫痫病史的25岁男性出现了右侧枕叶癫痫发作和进行性右侧同向性偏盲。磁共振成像显示左侧颞顶枕白质弥漫性强化以及左侧颞叶内侧皮质增厚。切除的颞叶显示皮质发育异常和血管发育异常，伴有近期缺血性坏死灶和慢性炎症，这可以解释临床病情恶化的原因。