Domínguez A, Latorre C, Pineda V, Margall N, Bou R, Fontanals D, Corretger J M, Sánchez F, Juncosa T, Santfeliu I, Benet J, Pons I, Martínez A, Ciruela P, Muñoz C, Fortea J, Lobera E, Mirelis B, Rello J, Renau J, Prats G, Salleras L
Servicio de Microbiología, Hospital Sant Joan de Déu, Barcelona.
Med Clin (Barc). 1999 Jan 16;112(1):5-9.
The purpose of this study was to find out the incidence and characteristics of H. influenzae type b invasive disease (HibID) in Catalonia, Spain.
An active surveillance of H. influenzae isolated from normally sterile sites was carried out during 1996. Microbiology laboratories of hospitals of Catalonia were periodically contacted by telephone. The serotype of all the strains was studied.
The incidence of H. influenzae invasive disease (HIID) was 7.1 per 100,000 in children under 5 years and 1.0 per 100,000 in those over 5 years. The incidence of serotype b was 6.4 per 100,000 children under 5 years and 0.2 above this age. Only three strains belonged to types other than b (d, e and f).
The incidence of HIbID is uncommon in Catalonia, lower than that registered in the prevaccine era in other countries and regions of the same geographical area.
本研究旨在查明西班牙加泰罗尼亚地区b型流感嗜血杆菌侵袭性疾病（HibID）的发病率及特征。
1996年对从通常无菌部位分离出的流感嗜血杆菌进行了主动监测。定期通过电话联系加泰罗尼亚地区医院的微生物实验室。研究了所有菌株的血清型。
5岁以下儿童流感嗜血杆菌侵袭性疾病（HIID）的发病率为每10万人7.1例，5岁以上人群为每10万人1.0例。b型血清型在5岁以下儿童中的发病率为每10万人6.4例，在该年龄以上为0.2例。只有三株菌株属于b型以外的其他类型（d、e和f）。
在加泰罗尼亚，HibID的发病率并不常见，低于同一地理区域其他国家和地区在疫苗接种前时代的记录。
