DeGraeve J, Vanroy J
J Chromatogr. 1976 Dec 22;129:171-9. doi: 10.1016/s0021-9673(00)87778-x.
Several barbiturates and other anticonvulsant drugs can be analyzed simultaneously as dimethylated derivatives by high-resolution gas chromatography with a solid flash methylation injector. Quantitative determinations were performed on test serum during a quality control scheme. The sensitivity (+/- 0.1 mug/ml) and the accuracy are compatible with the measurement of therapeutic levels of barbiturates. The advantages of the method are discussed.
几种巴比妥酸盐和其他抗惊厥药物可以通过带有固体快速甲基化进样器的高分辨率气相色谱法同时作为二甲基化衍生物进行分析。在质量控制方案期间对测试血清进行了定量测定。该方法的灵敏度（±0.1微克/毫升）和准确度与巴比妥酸盐治疗水平的测量相匹配。讨论了该方法的优点。
