Haqqani M T, Fox H
J Clin Pathol. 1976 Nov;29(11):959-66. doi: 10.1136/jcp.29.11.959.
An adenosquamous carcinoma of the endometrium is one which contains both malignant glandular and malignant squamous components; such tumours are considered rare in Britain but are thought to account for nearly one-third of all endometrial neoplasms in the United States. A survey of 675 cases of endometrial cancer seen during the period 1956-75 showed that the incidence of adenosquamous carcinoma was 5%, an incidence that remained static during this 20-year period. The principal difficulties encountered in the diagnosis of these neoplasms are in identifying the squamous component as such and in differentiating it from benign metaplastic squamous epithelium. The prognosis for patients with an endometrial adenosquamous carcinoma is very much worse than for women with a pure adenocarcinoma, and because these neoplasms are often wrongly identified it is possible that the currently accepted prognoses for both pure adenocarcinoma and adenoacanthoma of the endometrium may have to be revised. There appears to be a true variation in the incidence of this neoplasm between Britain and the United States.
子宫内膜腺鳞癌是一种同时包含恶性腺性成分和恶性鳞状成分的癌症；这类肿瘤在英国被认为很罕见，但在美国据信占所有子宫内膜肿瘤的近三分之一。一项对1956年至1975年期间所见的675例子宫内膜癌病例的调查显示，腺鳞癌的发病率为5%，这一发病率在这20年期间保持稳定。诊断这些肿瘤时遇到的主要困难在于识别鳞状成分本身以及将其与良性化生鳞状上皮区分开来。子宫内膜腺鳞癌患者的预后比单纯腺癌女性的预后差得多，而且由于这些肿瘤常常被错误识别，目前公认的子宫内膜单纯腺癌和腺棘皮癌的预后可能不得不进行修订。在英国和美国，这种肿瘤的发病率似乎存在真正的差异。
