阻塞性肝病患者血清碱性磷酸酶同工酶谱的解读
An interpretation of the serum alkaline phosphatase isoenzyme patterns in patients with obstructive liver disease.
作者信息
Price C P, Sammons H G
出版信息
J Clin Pathol. 1976 Nov;29(11):976-80. doi: 10.1136/jcp.29.11.976.
Abstract
Earlier studies have identified two main isoenzymes of alkaline phosphatase in the sera of patients with obstructive liver disease. This paper reports on a study of these isoenzymes in specific types of liver disease where the pathology in relation to bile duct obstruction is known. The results have been used to support the theory that in biliary obstruction the increase in serum alkaline phosphatase is in part due to regurgitation of the biliary isoenzymes.
摘要
早期研究已在梗阻性肝病患者血清中鉴定出碱性磷酸酶的两种主要同工酶。本文报道了一项针对特定类型肝病中这些同工酶的研究，其中与胆管梗阻相关的病理情况是已知的。这些结果被用于支持以下理论：在胆道梗阻中，血清碱性磷酸酶升高部分归因于胆汁同工酶的反流。
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An interpretation of the serum alkaline phosphatase isoenzyme patterns in patients with obstructive liver disease.阻塞性肝病患者血清碱性磷酸酶同工酶谱的解读
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本文引用的文献
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The origin of elevation of serum alkaline phosphatase in hepatic disease. An experimental study.肝病时血清碱性磷酸酶升高的起源。一项实验研究。
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Serum alkaline phosphatase fractions in hepato-biliary and bone diseases.肝胆疾病和骨病中的血清碱性磷酸酶组分
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The effects of experimental acute biliary obstruction and release on the rat liver. A histochemical study.实验性急性胆道梗阻及解除对大鼠肝脏的影响。一项组织化学研究。
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Serum alkaline phosphatase activity in diseases of the skeletal and hepatobiliary systems. A consideration of the current status.骨骼和肝胆系统疾病中的血清碱性磷酸酶活性。现状考量
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Intrahepatic cholestasis (cholangiolitis).肝内胆汁淤积（胆小管炎）。
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Estimation of plasma phosphatase by determination of hydrolysed phenol with amino-antipyrine.通过用氨基安替比林测定水解苯酚来估算血浆磷酸酶。
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An assessment of 5'-nucleotidase as a liver-function test.5'-核苷酸酶作为肝功能检测指标的评估
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[Phosphatases. V. Intracellular distribution of alkaline phosphatase isoenzymes in the rat liver and their behavior following ligation of the ductus choledochus].[磷酸酶。V. 大鼠肝脏中碱性磷酸酶同工酶的细胞内分布及其在胆总管结扎后的变化]
Hoppe Seylers Z Physiol Chem. 1967 Oct;348(10):1311-8.
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A comparative study of alkaline phosphatase enzymes using starch-gel electrophoresis and sephadex gel-filtration with special reference to high molecular weight enzymes.
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