Price C P, Sammons H G
J Clin Pathol. 1976 Nov;29(11):976-80. doi: 10.1136/jcp.29.11.976.
Earlier studies have identified two main isoenzymes of alkaline phosphatase in the sera of patients with obstructive liver disease. This paper reports on a study of these isoenzymes in specific types of liver disease where the pathology in relation to bile duct obstruction is known. The results have been used to support the theory that in biliary obstruction the increase in serum alkaline phosphatase is in part due to regurgitation of the biliary isoenzymes.
早期研究已在梗阻性肝病患者血清中鉴定出碱性磷酸酶的两种主要同工酶。本文报道了一项针对特定类型肝病中这些同工酶的研究,其中与胆管梗阻相关的病理情况是已知的。这些结果被用于支持以下理论:在胆道梗阻中,血清碱性磷酸酶升高部分归因于胆汁同工酶的反流。