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[心因性阳痿的新动物模型:社会应激诱发交配障碍的行为学研究方法]

[New animal models for psychogenic impotence: an ethological approach to copulatory disorder induced by social stress].

作者信息

Yoshimura H

机构信息

Behavioral Pharmacology Laboratory, Faculty of Health Sciences, Ehime University School of Medicine, Japan.

出版信息

Nihon Shinkei Seishin Yakurigaku Zasshi. 1998 Oct;18(5):169-80.

PMID:10028488
Abstract

Although various experimental models of mental illness, such as anxiety and depression, have been developed, little attention has been paid to male psychogenic impotence. Since sociopsychological factors are presumed to play an important role in many cases of human impotence, an animal model of psychogenic impotence is needed to satisfy such validity. From an ethological viewpoint, we have recently developed new animal models for psychogenic impotence using sociopsychological manipulations, that is, social deprivation and social conflict. This review focused only on the methodology and the actions of drugs on such copulatory disorder induced by social stress. Possible brain mechanisms underlying stress-induced copulatory disorder were also considered.

摘要

尽管已经开发出各种精神疾病的实验模型,如焦虑和抑郁,但男性心因性阳痿却很少受到关注。由于社会心理因素被认为在许多人类阳痿病例中起重要作用,因此需要一种心因性阳痿的动物模型来满足这种有效性。从行为学的角度来看,我们最近利用社会心理操纵,即社会剥夺和社会冲突,开发了新的心因性阳痿动物模型。这篇综述仅关注方法以及药物对这种由社会压力引起的交配障碍的作用。还考虑了压力诱导的交配障碍潜在的脑机制。

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