Govind C K, Lang F
J Comp Neurol. 1976 Dec 15;170(4):421-33. doi: 10.1002/cne.901700403.
The conduction velocity and axon diameter of medial and lateral giant axons in lobsters was followed during growth from early juvenile (13 mm) to adult (250 mm) forms. In both axons, conduction velocity increased more than 4-fold in the growth period examined. Correlated with the increase in conduction velocity is an increase in axon diameter and the relationship between these two parameters is expressed by the equation CV = krX, where X equals 0.5 for the lateral and 0.7 for the medial giant axons. The sheath surrounding the giant axons also increases in size during growth with that of the medial giant axon being considerably thicker than that of the lateral giant axon. The significance of the increase in axon diameters is to increase conduction velocity and thereby reduce the latency of the escape response mediated by these giant axons.
在龙虾从幼年早期（13毫米）生长到成年期（250毫米）的过程中，对其内侧和外侧巨轴突的传导速度和轴突直径进行了跟踪研究。在研究的生长阶段，这两种轴突的传导速度均增加了4倍以上。与传导速度增加相关的是轴突直径的增加，这两个参数之间的关系由方程CV = krX表示，其中外侧巨轴突的X等于0.5，内侧巨轴突的X等于0.7。巨轴突周围的鞘在生长过程中也会增大，内侧巨轴突的鞘比外侧巨轴突的鞘厚得多。轴突直径增加的意义在于提高传导速度，从而减少由这些巨轴突介导的逃避反应的潜伏期。
