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卡马西平治疗智力障碍患者的癫痫

Carbamazepine in the treatment of epilepsy in people with intellectual disability.

作者信息

Waisburg H, Alvarez N

机构信息

Wrentham Developmental Center, Massachusetts 02093, USA.

出版信息

J Intellect Disabil Res. 1998 Dec;42 Suppl 1:36-40.

Abstract

Carbamazepine is a major antiepileptic drug which is primarily used to treat epileptic patients suffering from partial seizures with or without secondary generalization, but which also has applications in those suffering from primary generalized tonic-clonic seizures. Besides its antiepileptic effect, carbamazepine is also indicated in the treatment of trigeminal and occipital neuralgia, and in manic depressive disorders. Because of its minimal unwanted effects on cognition and behaviour, carbamazepine is an excellent drug for the treatment of people with intellectual disability and epilepsy. Carbamazepine is still one of the most commonly prescribed medications in the treatment of epileptic disorders.

摘要

卡马西平是一种主要的抗癫痫药物,主要用于治疗患有部分性发作(伴有或不伴有继发性全身性发作)的癫痫患者,但也适用于患有原发性全身性强直阵挛发作的患者。除了抗癫痫作用外,卡马西平还可用于治疗三叉神经痛和枕神经痛以及躁狂抑郁症。由于其对认知和行为的不良影响极小,卡马西平是治疗智障和癫痫患者的理想药物。卡马西平仍然是治疗癫痫疾病最常用的药物之一。

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