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卡马西平治疗智力障碍患者的癫痫

Carbamazepine in the treatment of epilepsy in people with intellectual disability.

作者信息

Waisburg H, Alvarez N

机构信息

Wrentham Developmental Center, Massachusetts 02093, USA.

出版信息

J Intellect Disabil Res. 1998 Dec;42 Suppl 1:36-40.

PMID:10030430
Abstract

Carbamazepine is a major antiepileptic drug which is primarily used to treat epileptic patients suffering from partial seizures with or without secondary generalization, but which also has applications in those suffering from primary generalized tonic-clonic seizures. Besides its antiepileptic effect, carbamazepine is also indicated in the treatment of trigeminal and occipital neuralgia, and in manic depressive disorders. Because of its minimal unwanted effects on cognition and behaviour, carbamazepine is an excellent drug for the treatment of people with intellectual disability and epilepsy. Carbamazepine is still one of the most commonly prescribed medications in the treatment of epileptic disorders.

摘要

卡马西平是一种主要的抗癫痫药物,主要用于治疗患有部分性发作(伴有或不伴有继发性全身性发作)的癫痫患者,但也适用于患有原发性全身性强直阵挛发作的患者。除了抗癫痫作用外,卡马西平还可用于治疗三叉神经痛和枕神经痛以及躁狂抑郁症。由于其对认知和行为的不良影响极小,卡马西平是治疗智障和癫痫患者的理想药物。卡马西平仍然是治疗癫痫疾病最常用的药物之一。

相似文献

1
Carbamazepine in the treatment of epilepsy in people with intellectual disability.卡马西平治疗智力障碍患者的癫痫
J Intellect Disabil Res. 1998 Dec;42 Suppl 1:36-40.
2
Use of antiepileptic drugs in the treatment of epilepsy in people with intellectual disability.抗癫痫药物在智力残疾人群癫痫治疗中的应用。
J Intellect Disabil Res. 1998 Dec;42 Suppl 1:1-15.
3
Phenytoin: effective but insidious therapy for epilepsy in people with intellectual disability.苯妥英钠:治疗智障人士癫痫有效但具潜在危害的疗法。
J Intellect Disabil Res. 1998 Dec;42 Suppl 1:24-31.
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Valproate in the treatment of epilepsy in people with intellectual disability.丙戊酸盐用于治疗智力残疾者的癫痫
J Intellect Disabil Res. 1998 Dec;42 Suppl 1:32-5.
5
Antiepileptic efficacy of vigabatrin in people with severe epilepsy and intellectual disability.
J Intellect Disabil Res. 1998 Dec;42 Suppl 1:46-9.
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Long-term effects of zonisamide in the treatment of epilepsy in children with intellectual disability.
J Intellect Disabil Res. 1998 Dec;42 Suppl 1:68-73.
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Barbiturates in the treatment of epilepsy in people with intellectual disability.
J Intellect Disabil Res. 1998 Dec;42 Suppl 1:16-23.
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[Decrease of folic acid and cognitive alterations in patients with epilepsy treated with phenytoin or carbamazepine, pilot study].[叶酸减少与苯妥英钠或卡马西平治疗的癫痫患者认知改变的初步研究]
Rev Invest Clin. 2005 Jul-Aug;57(4):522-31.
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The relationship among side effects associated with anti-epileptic medications in those with intellectual disability.智力障碍患者抗癫痫药物相关副作用之间的关系。
Res Dev Disabil. 2011 Sep-Oct;32(5):1646-51. doi: 10.1016/j.ridd.2011.02.015. Epub 2011 Apr 1.
10
Prolonged use of phenytoin, carbamazepine or valproate monotherapy on plasma levels of folate and B(12): a comparison between epileptic patients with or without cardiovascular disorders.苯妥英、卡马西平或丙戊酸单药长期使用对叶酸和维生素B12血浆水平的影响:有或无心血管疾病的癫痫患者之间的比较
Neuro Endocrinol Lett. 2006 Feb-Apr;27(1-2):85-8.

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