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帕金森病中的2,3-二磷酸甘油酸

2,3 diphosphoglycerate in Parkinson's disease.

作者信息

Alevizos B, Stefanis C

出版信息

J Neurol Neurosurg Psychiatry. 1976 Oct;39(10):952-7. doi: 10.1136/jnnp.39.10.952.

DOI:10.1136/jnnp.39.10.952
PMID:1003241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC492497/
Abstract

The red cell 2,3 DPG, the most important factor for oxygen delivery in the tissues, was found to be increased in Parkinsonism patients compared with controls. The aging process seems not to be a factor in the increased 2,3 DPG concentration. Other factors relevant to raised 2,3 DPG level such as physical activity, increased oxygen requirements, and metabolic changes are discussed.

摘要

红细胞2,3-二磷酸甘油酸（2,3 DPG）是组织中氧输送的最重要因素，研究发现帕金森病患者的红细胞2,3 DPG水平相较于对照组有所升高。衰老过程似乎并非导致2,3 DPG浓度升高的因素。文中还讨论了与2,3 DPG水平升高相关的其他因素，如体力活动、氧需求增加以及代谢变化。