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巨型艾美耳球虫在穿透培养细胞过程中,其棒状体可能具有的分泌功能。

Possible secretory function of the rhoptries of Eimeria magna during penetration of cultured cells.

作者信息

Jensen J B, Edgar S A

出版信息

J Parasitol. 1976 Dec;62(6):988-92.

PMID:1003289
Abstract

Ultrastructure of the penetration of Eimeria magna sporozoites into embryonic bovine trachea cells demonstrated that the host cell membrane was not broken during entry of the parasite. This membrane did, however, undergo alterations characterized by blebbing of vesicles, thickening, and eventual disorganization once penetration was completed. Concurrent with the entrance of the parasite into the cell, and the subsequent membrane alterations, was the appearance of empty membrane saccules, probably rhoptries, in the apical region of the sporozoite. It was proposed that rhoptry secretions aided penetration by changing cell surface characteristics which produced an eventual breakdown of the invaginated protion of the host cell membrane.

摘要

巨型艾美耳球虫子孢子侵入胚胎期牛气管细胞的超微结构显示,在寄生虫进入过程中宿主细胞膜未破裂。然而,一旦穿透完成,该膜确实会发生变化,其特征为小泡形成、增厚,最终结构紊乱。与寄生虫进入细胞以及随后的膜变化同时发生的是,在子孢子顶端区域出现了空的膜泡,可能是棒状体。有人提出,棒状体分泌物通过改变细胞表面特征来辅助穿透,这最终导致宿主细胞膜内陷部分的破裂。

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J Parasitol. 1976 Dec;62(6):988-92.
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