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柔嫩艾美耳球虫子孢子棒状体蛋白的特性：艾美耳属物种内以及单一物种柔嫩艾美耳球虫三个无性生殖世代中棒状体表位的抗原多样性。

Characterization of rhoptry proteins of Eimeria tenella sporozoites: antigenic diversity of rhoptry epitopes within species of the genus Eimeria and among three asexual generations of a single species, E. tenella.

作者信息

Tomley F M

机构信息

Institute for Animal Health, Compton, Newbury, Berkshire, United Kingdom.

出版信息

Infect Immun. 1994 Oct;62(10):4656-8. doi: 10.1128/iai.62.10.4656-4658.1994.

DOI:10.1128/iai.62.10.4656-4658.1994
PMID:7523296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC303160/
Abstract

Rhoptry organelles from sporozoites of the apicomplexan parasite Eimeria tenella contain at least 60 independent polypeptides that can be resolved by two-dimensional gel electrophoresis. Rhoptries from three species of Eimeria that infect chickens share very few antibody cross-reactive epitopes, and there is poor conservation of epitopes among three distinct asexual generations of zoites within the developmental life cycle of a single parasite, E. tenella.

摘要

顶复门寄生虫柔嫩艾美耳球虫子孢子的棒状体细胞器含有至少60种独立的多肽，这些多肽可通过双向凝胶电泳进行分离。感染鸡的三种艾美耳球虫的棒状体具有非常少的抗体交叉反应表位，并且在单个寄生虫柔嫩艾美耳球虫发育生命周期内的三个不同无性世代的子孢子中，表位的保守性很差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6080/303160/c7328f416a98/iai00010-0571-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6080/303160/1bfffd0908fc/iai00010-0571-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6080/303160/318e781a0bbd/iai00010-0571-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6080/303160/c7328f416a98/iai00010-0571-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6080/303160/1bfffd0908fc/iai00010-0571-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6080/303160/318e781a0bbd/iai00010-0571-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6080/303160/c7328f416a98/iai00010-0571-c.jpg

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本文引用的文献

1
Rhoptry organelles of apicomplexan parasites.顶复门寄生虫的棒状体细胞器。
Parasitol Today. 1992 Jan;8(1):28-32. doi: 10.1016/0169-4758(92)90308-o.
2
CD8+ T cell-coccidia interactions.
Parasitol Today. 1994 Jan;10(1):10-4. doi: 10.1016/0169-4758(94)90347-6.
3
Biogenesis of rhoptry organelles in Plasmodium falciparum.恶性疟原虫中棒状体细胞器的生物发生
Mol Biochem Parasitol. 1993 Feb;57(2):269-79. doi: 10.1016/0166-6851(93)90203-a.
球虫病：该物种免疫生物学的最新进展、预防措施以及疫苗接种作为对抗这些顶复门寄生虫的控制工具的重要性。
Vet Med (Auckl). 2014 Apr 28;5:23-34. doi: 10.2147/VMRR.S57839. eCollection 2014.
4
Life cycle stages, specific organelles and invasion mechanisms of species.物种的生命周期阶段、特定细胞器和入侵机制。
Parasitology. 2020 Mar;147(3):263-278. doi: 10.1017/S0031182019001562. Epub 2019 Nov 18.
5
From the Macro to the Micro: Gel Mapping to Differentiate between Sporozoites of Two Immunologically Distinct Strains of Eimeria maxima (Strains M6 and Guelph).从宏观到微观：凝胶图谱法区分两种免疫特性不同的巨型艾美耳球虫菌株（M6 菌株和圭尔夫菌株）的子孢子
PLoS One. 2015 Dec 7;10(12):e0143232. doi: 10.1371/journal.pone.0143232. eCollection 2015.
6
Development of Eimeria nieschulzi (Coccidia, Apicomplexa) Gamonts and Oocysts in Primary Fetal Rat Cells.尼氏艾美耳球虫（球虫纲，顶复门）配子体和卵囊在原代胎鼠细胞中的发育
J Parasitol Res. 2013;2013:591520. doi: 10.1155/2013/591520. Epub 2013 Jun 19.
7
Toxoplasma rhoptries: unique secretory organelles and source of promising vaccine proteins for immunoprevention of toxoplasmosis.弓形虫棒状体：独特的分泌细胞器及用于弓形虫病免疫预防的潜在疫苗蛋白来源
J Biomed Biotechnol. 2008;2008:632424. doi: 10.1155/2008/632424.
8
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9
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Clin Microbiol Rev. 2002 Jan;15(1):58-65. doi: 10.1128/CMR.15.1.58-65.2002.
10
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4
Characterisation of a family of multi-copy genes encoding rhoptry protein homologues in Babesia bovis, Babesia ovis and Babesia canis.牛巴贝斯虫、绵羊巴贝斯虫和犬巴贝斯虫中编码棒状体蛋白同源物的多拷贝基因家族的特征分析
Mol Biochem Parasitol. 1993 Feb;57(2):181-92. doi: 10.1016/0166-6851(93)90194-3.
5
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6
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7
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8
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Infect Immun. 1993 Aug;61(8):3511-7. doi: 10.1128/iai.61.8.3511-3517.1993.
9
Analysis of the high molecular weight rhoptry complex of Plasmodium falciparum using monoclonal antibodies.
Parasitology. 1994 Apr;108 ( Pt 3):269-80. doi: 10.1017/s0031182000076113.
10
Monoclonal antibody characterization of Plasmodium falciparum antigens.恶性疟原虫抗原的单克隆抗体特性分析
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