• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

锌给药对小鼠L1210和BW5147肿瘤生长的影响。

Effect of zinc administration on the growth of L1210 and BW5147 tumors in mice.

作者信息

Phillips J L, Sheridan P J

出版信息

J Natl Cancer Inst. 1976 Aug;57(2):361-3. doi: 10.1093/jnci/57.2.361.

DOI:10.1093/jnci/57.2.361
PMID:1003517
Abstract

Aqueous zinc acetate injected ip prevented tumor growth in 50-70% of BDF male mice previously inoculated ip with L1210 leukemia cells. However, aqueous zinc acetate injected sc did not prevent tumor growth in AKR/J mice inoculated im with BW5147 lymphatic leukemia cells. In the latter mice, only a small but statistically significant increase in mean survival was noted.

摘要

腹腔注射醋酸锌水溶液可使先前腹腔接种L1210白血病细胞的50%-70%的BDF雄性小鼠肿瘤生长受到抑制。然而,皮下注射醋酸锌水溶液并不能抑制肌肉注射BW5147淋巴白血病细胞的AKR/J小鼠的肿瘤生长。在后者的小鼠中,仅观察到平均生存期有微小但具有统计学意义的延长。

相似文献

1
Effect of zinc administration on the growth of L1210 and BW5147 tumors in mice.锌给药对小鼠L1210和BW5147肿瘤生长的影响。
J Natl Cancer Inst. 1976 Aug;57(2):361-3. doi: 10.1093/jnci/57.2.361.
2
Optimum time sequence for the administration of vincristine and cyclophosphamide in vivo.
Cancer Res. 1974 Aug;34(8):1857-61.
3
[Effect of Brucella abortus infection on the development of Rauscher and L1210 leukemias in mice].[流产布鲁氏菌感染对小鼠劳斯氏及L1210白血病发展的影响]
Vopr Virusol. 1973 Nov-Dec;18(6):728-31.
4
In vivo enhancement of 5-fluorouracil cytotoxicity to AKR leukemia cells by thymidine in mice.小鼠体内胸苷增强5-氟尿嘧啶对AKR白血病细胞的细胞毒性作用
J Natl Cancer Inst. 1978 Sep;61(3):843-7.
5
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.AKR淋巴瘤与人类血液肿瘤的化疗比较
Cancer Res. 1974 Jan;34(1):184-93.
6
Characteristics and response to certain cancer chemotherapeutic agents of an acute lymphocytic leukemia arising in a BALB-c times DBA-2F1 mouse.一只BALB-c×DBA-2F1小鼠发生的急性淋巴细胞白血病的特征及对某些癌症化疗药物的反应
Cancer Res. 1974 Aug;34(8):1866-9.
7
Potentiation of actinomycin D or adriamycin antitumor activity with DNA.放线菌素D或阿霉素与DNA联合增强抗肿瘤活性。
Cancer Res. 1976 Feb;36(2 Pt 1):496-504.
8
Anti-cancer activity of the extracts of stem and leaf of Tylophora indica.
Indian J Med Res. 1972 Mar;60(3):359-62.
9
[Antileukemic activity of carminomycin complexes with a high-polymer DNA].[柔红霉素与高分子DNA复合物的抗白血病活性]
Antibiotiki. 1980 Jun;25(6):454-8.
10
Tumorigenicity and anti-cancer properties of n-hydroxy urethan.N-羟基尿烷的致瘤性和抗癌特性
Indian J Cancer. 1974 Dec;11(4):462-6.

引用本文的文献

1
Zinc and gastrointestinal disease.锌与胃肠道疾病
World J Gastrointest Pathophysiol. 2014 Nov 15;5(4):496-513. doi: 10.4291/wjgp.v5.i4.496.
2
Magnesium (and trace substance) deficiencies in the pathogenesis of cancer.癌症发病机制中的镁(和痕量物质)缺乏。
Biol Trace Elem Res. 1979 Dec;1(4):273-97. doi: 10.1007/BF02778831.
3
Induction of hepatic metallothionein I in tumour-bearing mice.荷瘤小鼠肝脏金属硫蛋白I的诱导
Br J Cancer. 1995 Apr;71(4):712-6. doi: 10.1038/bjc.1995.139.
4
Metal interactions in carcinogenesis: enhancement, inhibition.金属在致癌过程中的相互作用:增强、抑制
Environ Health Perspect. 1981 Aug;40:65-81. doi: 10.1289/ehp.814065.
5
The role of zinc in 5',5'-diadenosine tetraphosphate production by aminoacyl-transfer RNA synthetases.锌在氨酰转移RNA合成酶产生5',5'-二磷酸腺苷过程中的作用。
Mol Cell Biochem. 1983;52(1):3-11. doi: 10.1007/BF00230583.